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Fig. 3 | Genetics Selection Evolution

Fig. 3

From: Selection signatures in tropical cattle are enriched for promoter and coding regions and reveal missense mutations in the damage response gene HELB

Fig. 3

Genomic feature enrichment in selective sweeps. a The strength of enrichment for 20 genomic features in 72 indicine-specific regions assessed by overlapping genomic regions [50]. b Intersection of the delta allele frequency (ΔAF) with functional annotations derived from the reference UMD3.1 bovine genome. The number of SNPs in ΔAF bins is indicated on the left, and the M-value (log2-fold change) of the relative frequencies of SNPs in each functional category (on the right). The black line shows the number of SNPs within each (ΔAF) bin. c Intersection of the delta allele frequency (ΔAF) with functional annotations from the predicted regulatory elements in the cattle genome [20] and publicly available experimental epigenetic marks [49] and Fr-AgENCODE [48]

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